To lessen the stress of bringing your new fish home, treat them with API MELAFIX Freshwater Fish Bacterial Infection Remedy to help prevent any bacterial infections. There is a chance that the fish you purchased is infected. Detecting disease, especially in its early stages, is notoriously challenging. API MELAFIX Freshwater Fish Bacterial Infection Remedy may be used to treat bacterial infections in fish and lessen the likelihood that the disease will spread to other fish in the aquarium. The introduction of disease-causing bacteria and a lack of sanitary conditions in the aquarium are the primary causes of bacterial infections. Injured and otherwise compromised fish are particularly vulnerable, even in aquariums that seem spotless. Fin and tail rot, eye cloud, pop eye, body slime, and mouth fungus are all bacterial illnesses that, if untreated, may damage tissue and organs to the point of death. Healing of open wounds, treatment of bacterial infections, and stimulation of re-growth of damaged fins and tissue may all be expected within a week of using API MELAFIX Freshwater Fish Bacterial Infection Remedy. Add 5 milliliters to every 10 gallons of aquarium water. It will not change the water’s pH or color, and it won’t harm the biological filter. Infected fish should be dosed once daily for 7 days, and then as needed following. Dose fresh fish twice a day for three days. If at all feasible, the activated carbon should be emptied from the filter before it is used. Whether your aquarium is saltwater, freshwater, or a reef, API Aquarium has the items you need to keep it looking its best.
API has spent more than half a century developing cutting-edge, science-based products that simplify aquarium maintenance. When used together, API’s aquarium treatments may effectively combat algae, encourage beneficial bacterial development, and treat fish ailments like ich and fin rot. They do their best to make the aquarium a comfortable, secure place for fish like cichlids, goldfish, and tropical community fish. Thanks to API, you can spend less time cleaning the aquarium and more time appreciating your fish. Use all items exactly as prescribed for the greatest results.

Features of the MELAFIX API
- Included is a single Application Programming Interface. The 16-ounce bottle of MELAFIX Freshwater Fish Bacterial Infection Remedy
- Cure for bacterial infections, broken fins, ulcers, and cuts
- Tea tree extract is a botanical ingredient that may aid fish in a short amount of time.
- Aids in medicating newly imported fish, which helps prevent the spread of illness in freshwater aquariums.
- When treating infections, use once daily for seven days, and when introducing new fish, use once daily for three days.
MELAFIX API User Manual
Shake it up and, if you can, take the activated carbon out of the filter. You should add 1 teaspoon (5 ml) for every 50 U.S. gallons (190 L) of aquarium water, or 1/4 cupful (60 ml) for every 600 U.S. gallons (2,271 L). As an illness or wound therapy, the aforementioned dosages should be taken daily for 7 days. Seven days later, replace 25% of the water. If required, therapy should be continued. There should be a three-day wait between introducing new fish and handling fish.
Fungal Infection | Fin And Tail Rot | Dropsy and Malawi Bloat | Bacterial Hemorrhagic Septicemia |
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*Whitish cottony tufts or patches appear on the mouth, skin and fins of tropical fish, goldfish and koi. *We recommend API PIMAFIX. | The fins have a torn and disheveled appearance. A fish’s fins and tail may deteriorate to the point that the animal dies of the disease. Fungal infections as a secondary infection are prevalent. API MELAFIX (or BETTAFIX if you have a betta fish), PIMAFIX, or FIN & BODY CURE are all great options. | Because fluid builds up within the fish’s body, it begins to seem bloated. When seen from the side, fish scales may sometimes seem like they protrude from the body. To the point that they float belly up, fish have lost the capacity to swim. We advise you to use API MELAFIX (or BETTAFIX if you have a betta fish), or PIMAFIX, or FIN & BODY CURE. | Fins and the body of the fish are stained with blood. API MELAFIX (or BETTAFIX if you have a betta fish), PIMAFIX, or FIN & BODY CURE are all great options. |
Eye Cloud, Body Slime | Open Red Sores | outh Fungus – Saddleback Disease | Bacterial Gill Disease |
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The eyes cloud over and/or bulge out of the skull. Fish have cloudy or slimy spots all over their body. Fish with parasites may scratch at the glass or other aquarium fixtures and breathe quickly. API MELAFIX (or BETTAFIX if you have a betta fish), PIMAFIX, or FIN & BODY CURE are all great options. | Red, raw sores may be seen all over the fish’s body. To treat your fish, try API MELAFIX (or BETTAFIX if you have a betta fish), PIMAFIX, E.M. ERYTHROMYCIN, or FIN & BODY CURE. | Fish have raised gray spots on their fins and mouths. Caused by grey patches that appear on the backs of live bearers like guppies and mollies, this condition is known as “saddle back illness.” Red ulcers may form on infected parts and spread to the gills, leading to a quick death for the fish. You may try E.M. ERYTHROMYCIN or FIN & BODY CURE, or we suggest API MELAFIX (or BETTAFIX if you have a betta fish) or PIMAFIX. | Scratching and lethargy are common reactions of fish to inanimate items. One possible side effect is the development of a grey coating on the skin. Fish that are hyperventilating may be seen gasping near the aquarium’s surface or resting on their bellies. Damage to the gills causes suffocation and eventually death. To treat your fish, try API MELAFIX (or BETTAFIX if you have a betta fish), PIMAFIX, E.M. ERYTHROMYCIN, or FIN & BODY CURE. |
Flukes/Parasitic Worms | Hole-In-The-Head Disease (Hexamita) | Ich (Ichthyophthirius) | Subclinical Parasitic Infestation |
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Parasitic worms are often invisible to the naked eye. Scratching and lethargy are common reactions of fish to inanimate items. The skin may begin to develop a grey coating. Fish that are hyperventilating may be seen gasping near the aquarium’s surface or resting on their bellies. Damage to the gills causes suffocation and eventually death. API GENERAL CURE is what you should use. MELAFIX (or BETTAFIX if you have a betta fish) and PIMAFIX should be used combined to treat secondary or fungal infections. | The skin and muscle surrounding the fish’s face become pitted and eroded, making the condition visible. Rather than occurring on the fish’s skin, this erosion seems to be caused by the parasite’s presence in the digestive system. Many fish lose their appetite, experience weight loss, and become agitated before dying if not treated. API GENERAL CURE is the one we suggest. | Fish with this virus display early signs including darting about the tank and clawing at the gravel and decorations. Fish may emerge near filters and aerators because they are having trouble breathing and the water is too polluted for them to swim deep. The fish could or might not have white patches. For the best results, use API SUPER ICK CURE in conjunction with API AQUA SEA SALT. | It’s possible for fish to scratch at aquarium decor. Fish may acquire slimy skin and/or grow fin clamps. There may be evidence of labored breathing. Both API SUPER ICK CURE and API AQUA SEA SALT come highly recommended. |
Products used in conjunction with the API MELAFIX
API MELAFIX | API PIMAFIX | API FIN & BODY CURE | E.M ERYTHROMYCIN | API SUPER ICK CURE | API AQUARIUM SALT | |
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Fin And Tail Rot | ✓ | ✓ | ✓ | Use in combination with medications | ||
Dropsy and Malawi Bloat | ✓ | ✓ | ✓ | Use in combination with medications | ||
Bacterial Hemorrhagic Septicemia | ✓ | ✓ | ✓ | Use in combination with medications | ||
Eye Cloud, Body Slime | ✓ | ✓ | ✓ | Use in combination with medications | ||
Open Red Sores | ✓ | ✓ | ✓ | ✓ | Use in combination with medications | |
Mouth Fungus – Saddleback Disease | ✓ | ✓ | ✓ | ✓ | Use in combination with medications | |
Subclinical Parasitic Infestation | Melafix & Pimafix used together | Melafix & Pimafix used together | ✓ | Use in combination with medications | ||
Ich (Ichthyophthirius) | ✓ | Use in combination with medications | ||||
Fungal Infection | ✓ | Use in combination with medications | ||||
Bacterial Gill Disease | ✓ | ✓ | ✓ | ✓ | Use in combination with medications |
Customer questions & answers
Question: Could this be used for fish quarantine?
Answer: It is recommended by the API that Melafix and Pimafix be used combined to cure flukes and parasitic worms, or that General Cure be used for 7 days; either way, bringing the temperature up to 85–86 degrees will also eliminate ICH along with the flukes and parasites. That accounts for every single one of them: Because heat and medications need a lot of oxygen, I do the same thing, but you really must add a few air stones. The water will be oxygenated and circulated thanks to the air stones. Use a few gallons of water in a container or tank, adjust the temperature of the water every day, and redose the same quantity each day. Parasites, germs, and fungi that have died in the water are all washed away when the whole tank is refilled every day. I have tried both, and although both the General Cure and heat are effective, I find that the General Cure works better for my QT. If the fish still have a skin issue after being treated with General Cure, then they should be quarantined for another 7 days with only Melafix and Pimafix. The temperature of the display tank should be raised to 85–86 degrees Fahrenheit for a week before any QT fish are transferred there to ensure that the new additions to the tank experience little stress. For me, this method always ensures a smooth transition with no ill effects on anybody involved.
Question: The 8-ounce bottle labeled itself as containing 1% melaleuca oil, whereas the 16-ounce bottle labeled itself as containing 1% pimenta oil.
Answer: The pimenta is more potent. They presumably envision a large tank with massive fish, but in reality, smaller species do just well in this setup.
Question: What happens to the water’s chemistry as a result of this? Has anybody seen an increase in Nitirite? In any case, I appreciate it.
Answer: The chemical composition of your water shouldn’t change.
Question: For a 4 gallon aquarium, how many drops would you recommend? I didn’t understand the directions, so I simply put in three drops:0
Answer: To be precise, use 0.5 ML for every gallon of water. A graduated eye dropper, such as one marked in milliliters (MLs), is the most accurate measuring tool. Check your medical cabinet for a discarded eye dropper; many over-the-counter medications for kids come with one, or you can get one up for next to nothing on sites like Amazon or eBay. For a 4 gallon tank, that’s 2 MLs’ worth.
- Use 1 teaspoon or 1 eyedropper per 10 gallons. 4.9 ML
- To treat 5 gallons, measure out 1/2 teaspoonful (or 2.4 mL using an eyedropper).
- Use a quarter teaspoon or 1.2 mL eyedropper for every 2.5 gallons.
- For every 1.25 gallons, add 1/8 teaspoon of salt or.6 mL of liquid using an eyedropper.
- For 1 liter, use a.48-milliliter (mL) eyedropper (round off to .5ML)
Question: Is it possible that this might be fatal to my plants?
Answer: We have goldfish in a pond in our backyard, and I’ve found that this product has no negative effects on the flora there.
Question: I was wondering if anybody has any idea how long the 64 ounces would last.
Answer: While I don’t believe it has a shelf life as long as it’s preserved correctly, I also wouldn’t use it on my prize fish if it had been sitting about for more than five to ten years.